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Neural Control of Sexual Function

Kevin E. McKenna, Ph.D.
Department of Physiology and Urology
Ph.D., Johns Hopkins School of Medicine


My research focuses on the spinal cord control of autonomic function, with a particular interest in the neural control of sexual function. This research involves an integrated approach, using modern neuroanatomical, neurophysiological, biochemical and pharmacological techniques.

Specific projects include:
  1. Identification of the somatic and autonomic afferents and efferents innervating pelvic organs, using retrograde tracing techniques.
  2. Study of the mechanisms of sexual reflexes in both male and female rats using a novel preparation.
  3. Analysis of the descending control of sexual function using physiological, pharmacological and anatomical techniques.
  4. Study of the neural control of prostatic secretion and prostatic growth using physiological, pharmacological, anatomical, and biochemical techniques.
  5. Analysis of the mechanisms of diabetic impotence.
Selected Publications:

McVary KT, Rathnau CH, McKenna KE 1996 Sexual dysfunction in the diabetic BB/WOR rat: A role of central neuropathy. American Journal of Physiology (in press).

McKenna KE, Marson L 1996 CNS cell groups involved in the control of the ischiocavernosus and bulbospongiosus muscles: A transneuronal tracing study using pseudorabies virus. Journal of Comparative Neurology (in press).

Coolen LM, Allard J, Truitt WA, McKenna KE. Central regulation of ejaculation. Physiol Behav. 2004 Nov 15;83(2):203-15.

McVary KT, McKenna KE. The relationship between erectile dysfunction and lower urinary tract symptoms: epidemiological, clinical, and basic science evidence. Curr Urol Rep. 2004 Aug;5(4):251-7.

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